Australian scientists discover probable cause of Alzheimer's

After analyzing the brains of mice with Alzheimer’s with genetic engineering techniques, this team of Australian scientists has discovered a new probable cause that causes this serious degenerative disease, according to the results of their research published in the scientific journal PLOS.

These are blood leaks in the brain that deposit particles that carry toxic proteins, the famous “beta-amyloid” whose high deposit in the brain is one of the basic characteristics of this type of dementia.

And the most important thing is that this discovery opens up new opportunities to find a treatment against this disease that already affects 46 million people around the world.

“While we previously knew that the hallmark of people living with Alzheimer’s disease was the progressive accumulation of deposits of toxic proteins within the brain called beta-amyloid, researchers did not know where the amyloid originated or why it originated. deposited in the brain, “explained John Mamo, a researcher at the Health Innovation Research Institute at Curtin University (Australia).

A new way

The discovery of this new “‘blood-to-brain pathway” may be key, because if we can control blood levels of amyloid lipoprotein and prevent its leakage to the brain, this opens the possibility of new treatments to prevent Alzheimer’s disease and thus being able to slow down memory leakage.

This new research has used an innovative genetic engineering technique to detect this new cause of Alzheimer’s in the brains of laboratory mice.

“Our study found that mouse models that produced amyloid lipoprotein in the liver suffered from inflammation in the brain, accelerated brain cell death and memory loss,” added Professor Mamo.

This research team stresses that even more studies are needed, but their finding shows that the abundance of these toxic protein deposits in the blood could be prevented through a person’s diet and, in addition, some medications could also attack, in a way specific protein amyloid, thus reducing your risk and slowing the progression of Alzheimer’s disease.

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