During the conference “International Covid Summit – care experiences from the world” organized by the League in the Senate, the use of drugs and therapies against the SARS-CoV-2 coronavirus for which scientific evidence is lacking was promoted. This is why ivermectin, hydroxychloroquine and hyperimmune plasma are considered ineffective and not recommended by health authorities.
Turn on notifications to receive updates on
The “International Covid Summit – care experiences from around the world“, A controversial meeting promoted by the League (the Northern League senators Roberta Ferrero and Alberto Bagnai participated) during which doctors, presumed experts and other figures from the open anti-vaccination positions, no mask and similar. As the high-sounding name suggests in the conference there has been talk of treatment and not of prevention, therefore it was not directly discussed vaccines, nevertheless the narration of the home care so much guy there no vax, calling into question medications e therapy that have not only been considered ineffective from the international scientific community, but in some cases even harmful for health. Against the COVID-19, the infection caused by the coronavirus SARS-CoV-2, during the meeting the emphasis was on ivermectina, hydroxychloroquine and also al plasma iperimmune, but there was no lack of references to the vitamin D, at the curcuma and other natural remedies not supported by any scientific evidence. The meeting, as well as by some political forces, was harshly criticized by scientists and virologists such as Roberto Burioni, who in a twitter on Twitter launched a real j’accuse. “While we find ourselves a serious health, social and economic danger, the Senate is hosting a conference where very dangerous lies are told and the use of drugs that are not only ineffective, but also very harmful are promoted. Someone has to answer for it ”, commented the virologist and science communicator of the San Raffaele University of Milan. This is why the drugs mentioned in the conference are not considered effective against SARS-CoV-2 coronavirus infection.
Among the most cited drugs in the no vax disinformation campaign is theivermectina, a pesticide and anthelmintic with properties antivirals which is mainly used in the ambit veterinarian. At the beginning of the pandemic, when it was not known how to fight COVID-19, doctors and scientists tried to test active ingredients they already had in the hopes they would be effective. Some laboratory studies such as “The FDA-approved Drug Ivermectin inhibits the replication of SARS-CoV-2 in vitro” published in Antiviral Research by Monash University researchers showed that ivermectin was able to neutralize the SARS-CoV-2 coronavirus in a test tube in the sun 48 ore. These investigations led to the organization of the first clinical trials (human tests), which however did not lead to the desired effects. In the study “Effect of Ivermectin on Time to Resolution of Symptoms Among Adults With Mild COVID-19 – A Randomized Clinical Trial” published in the journal Jama, for example, it was shown that the pesticide it does not reduce the duration of symptoms of the infection. In practice, it is ineffective. The study “Ivermectin for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials” also concluded that ivermectin does not reduce mortality, the duration of hospitalization and the clearance virale in infected patients. In light of these and other findings, the European Medicines Agency (EMA), la Food and Drug Administration (FDA) and other international health agencies have decided to not recommend this drug for patients with COVID-19. Nevertheless, the antivaccinisti they went on to argue that the drug’s effectiveness was “withheld” because a low cost; in practice, he would not have earned enough le pharmaceutical companies as the vaccine. So many have decided to self-administer ivermectin in horse doses, both to prevent and “cure” COVID-19, inevitably ending up in the hospital with a poisoning. In the United States, emergency calls for ivermectin poisoning during the pandemic have increased by several dozen every day, as told ABCNews by Dr. Julie Weber, who chairs the American Association of Poison Centers and director of the Missouri Poison Center. If this were not enough, recently one of the research that had “demonstrated” the effectiveness of ivermectin on people was withdrawn because it was full of errors and data specifically manipulated by the authors. However, this drug should not be demonized; it is in fact extremely effective in veterinary medicine and to combat some parasitic diseases come onchocerciasis e lymphatic filariasis (so much so that the discoverers of the active ingredient have been awarded the Nobel Prize), however it is not effective against COVID-19 and no health authority recommends it.
L’hydroxychloroquine antimalarial was probably the most discussed drug during the COVID-19 pandemic. Initially it was considered as a real lifesaver, especially after some studies conducted in France, but in the end it “collapsed” under the weight of the results of numerous scientific researches that have shown its ineffectiveness as an anti Covid drug . Without forgetting the plethora of side effects (from suicide risk to heart problems) emerged from the multiple investigations, conducted especially during the first phase of the pandemic. In the document “A living WHO guideline on drugs to prevent covid-19” published in the authoritative scientific journal The British Medical Journal, the World Health Organization (WHO) stresses that the drug should not be used to prevent disease since in clinical trials “with high certainty” hydroxychloroquine “had no significant effect on death and hospitalization”. There is also “moderate certainty” in Covid patients that the drug “had no significant effect on laboratory confirmed SARS-Cov-2 infection.” In the study “Hydroxychloroquine as pre-exposure prophylaxis for COVID-19 in healthcare workers: a randomized trial” published in the scientific journal Clinical Infectious Disiases it was shown that hydroxychloroquine does not prevent COVID-19 in healthcare workers, a category particularly exposed to risk of contagion. In the “Randomized Evaluation of COVid-19 thERapY (RECOVERY) Trial on hydroxychloroquine” study, hydroxychloroquine was administered to more than 1500 serious patients hospitalized with COVID-19, and their clinical outcomes were compared with those of another group not treated with the antimalarial. Within one month of administration he passed away on 25.7 percent of patients of the hydroxychloroquine group and the 23.5 percent of the non-drug group. This demonstrates the total ineffectiveness in preventing mortality. In the study “Treatment of COVID-19 Cases and Chemoprophylaxis of Contacts as Prevention (HCQ4COV19)” conducted in Spain, however, there was no difference in the course of COVID-19 in thousands of patients treated with or without the drug. In short, there is no scientific evidence on the efficacy of the drug against SARS-CoV-2 coronavirus infection, and for this reason it is not recommended for treating patients, nor for the prevention of the disease.
Vaccini, Fontana: “In Lombardy from 20 September the administration of the third dose will start”
The hyperimmune plasma
The plasma iperimmune (i.e. rich in neutralizing antibodies) obtained from patients convalescent / recovered COVID-19 has long been considered another precious weapon to fight the pandemic, nevertheless, even in this case, scientific evidence has decreed the exact opposite. The use of this method was definitively sunk by the recent and in-depth study “Early Convalescent Plasma for High-Risk Outpatients with Covid-19” published in the scientific journal The New England Journal of Medicine (NeMJ), among the most authoritative ever. worldwide in the health sector. Scientists from the National Heart, Lung, and Blood Institute of Bethesda and the University of Pittsburgh, comparing the clinical outcomes of plasma-treated or untreated nasopharyngeal swab positive patients determined that plasma was hyperimmune it does not reduce the risk of progression to severe COVID-19, even if it is administered within the first week from the onset of symptoms. Among the hundreds of patients involved in the study, aggravation occurred in 30 percent of patients given plasma and 31.9 percent of the group. placebo, a statistically irrelevant difference. Recently, the American National Institutes of Health (NIH) interrupted a study based on the experimentation of hyperimmune plasma, precisely because of the lack of benefits highlighted by the data. The Italian TSUNAMI study conducted in collaboration between the Istituto Superiore della Sanità (ISS) and the Italian Medicines Agency (AIFA) also demonstrated that hyperimmune plasma does not reduce the risk of respiratory aggravation e death in Covid patients with pneumonia and ventilatory impairment (mild to moderate). All these investigations, therefore, confirm the reason why the drugs and therapies presented at theInternational Covid Summit held in the Senate are not considered effective and are not recommended against COVID-19.