What is happening in the UK with the Delta variant and why the vaccinated also die

Around the 15th of May the Delta variant O VOC-21APR-02 (ex second Indian B.1.617.2) became the dominant one in UK, after passing the Alpha variant (ex English B.1.1.7) at the root of the dramatic surge in cases and deaths last winter. Based on new data from Public Health England (PHE), the government agency of the UK’s Department of Health and Welfare, up to 96 percent of new infections are caused by the Delta variant, whose cases double between every 4.5 and 11.5 days, depending on the region affected. Greater Manchester and Lancashire are the most affected counties, while the cities with the most significant outbreaks are Leicester, Hounslow and Bolton. British experts believe that this variant has one transmissibility 60 percent higher than the Alfa variant; it is no coincidence that new infections increased from 29,892 to 42,323 in one week, also leading to an increase (kept at bay by the vaccination campaign) in the number of hospitalized e deaths because of COVID-19, the infection caused by the SARS-CoV-2 coronavirus. Although to a lesser extent, patients were also involved fully vaccinated.

The PHE data cited by the Guardian indicate that around 33,000 cases of Delta variant infection were recorded in Great Britain between the beginning of February and the beginning of June; just under 20,000 occurred in unvaccinated subjects, 7,500 in those who had received a single dose of the vaccine and 1,800 in those who had received the double dose. As is known from clinical studies, a single dose of Covid’s vaccine AstraZeneca (Vaxzevria) or di Pfizer-BioNTech (Comirnaty) has an efficacy around the 30 percent against asymptomatic Delta variant infection, while 14 days after the second dose, protection rises to 66.1 percent for AstraZeneca and 93.4 percent for Pfizer’s mRNA vaccine. No vaccine is 100 percent effective, so it’s no wonder that some fully vaccinated people can get infected and even seriously ill.

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Among the 383 people hospitalized diagnosed with Delta variant coronavirus infection, 251 (65 percent) were not vaccinated; 86 (22 percent) received a single dose and 42 (10 percent) received two doses of the vaccine. Of all the hospitalized patients, 42 lost their lives one month after the diagnosis of positivity: 23 (54 percent) were not vaccinated; 12 (28 percent) were fully vaccinated and 7 (16 percent) had received only one dose. These data indicate that even those who have received the vaccine can become seriously ill and lose their lives from COVID-19, although this is a very low percentage (however predicted by experts). This is also demonstrated by the latest data released by the Centers for Disease Control and Prevention (CDC) Americans, according to which, out of about 100 million people completely immunized (as of 30 April 2021), 10 thousand were infected with the coronavirus, a thousand were hospitalized and 2 percent lost their lives (but not always for causes related to the pandemic pathogen).

“We expect to have occasional infections in vaccinees,” Dr. William Schaffner, a vaccine specialist at Vanderbilt University in Nashville, told the New York Times. “There is no vaccine in history that has ever been 100% effective. Vaccination is the best option available to us to avoid serious and critical illnesses. Just as it is also true that not everything in medicine is perfect ”, echoed Professor Paul Offit, director of the Vaccine Education Center at the Children’s Hospital of Philadelphia. The Delta variant that is circulating in the UK is more transmissible and potentially more aggressive and virulent than that Alpha it has supplanted, therefore it is not surprising that a small number of people, even if vaccinated, cannot win the battle with the virus.

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